International severe asthma registry (ISAR): protocol for a global registry
FitzGerald J. M, et al. BMC Med Res Methodol 2020. Available online.
Aiming to offer a rich source of real-life data for scientific research to understand and improve disease burden, treatment patterns and outcomes in patients with severe asthma, this paper describes the protocol for the development and management of the multi-disciplinary ISAR initiative.
Characterization of Severe Asthma Worldwide: Data from the International Severe Asthma Registry (ISAR)
Wang E, et al. CHEST 2020;157(4):790-804
To date, clinical characteristics of the international severe asthma population are unknown. This paper describes the demographic and clinical characteristics of patients managed in severe asthma services in the US, Europe, and Asia/Pacific region.
International Severe Asthma Registry: Mission Statement
The ISAR Study Group. CHEST 2020;157(4):805-814
The International Severe Asthma Registry (ISAR) is the first global adult severe asthma registry. It is a joint initiative where national registries (both newly created and pre-existing) retain ownership of their own data but open their borders and share data with ISAR for ethically-approved research purposes. This paper fully describes how ISAR may improve our understanding of severe asthma.
Development of the International Severe Asthma Registry (ISAR): A Modified Delphi Study
Bulathsinhala L, et al. J Allergy Clin Immunol Pract 2019; 7(2): 578-588.e2
Getting 27 experts to agree on anything is impressive! This paper describes the process of reaching consensus on which core variables to collect in ISAR.