Collaboration Partners

Optimum Patient Care (OPC) Global

  • Co-sponsorship, Project Management and Delivery
  • Co-funding the initial setup of ISAR ( 50%)
  • Data standardization, eCRF, processing, hosting and guardianship

OPC Global: A research organisation with 10 years of experience. OPC Global Has successfully collaborated with renowned research institutes globally contributing towards the delivery of over 48 research projects and publications. It is an contributor of OPCRD academic research and collaborations.

The OPC Team

David Price – Chief Scientist & Global Engagement


Victoria Carter – Sponsor Engagement Lead

Chris Price – Legal & Contracting Lead

Ruth Murray – Publication Lead

Nevaashni Eleangovan – Operations Lead

Anne-Frieda Taurel – Senior Epidemiologist


Anthony Newell – Research Analytics Manager


Brooklyn Stanley – Data Lead


Amy Pickering – Country Coordinator

Aby Srikanth – Project Administrator


Julie-Anne Cook – Project Administrator 


Nasloon Ali – Researcher

Audrey Ang – Research Programme Communications Lead

Amber Chung – Data Scientist

Chester Gan – Data Scientist

Laura Liu – Data Scientist

Indu Joshi  – Junior Data Analyst

Jam Tabio – Junior Data Analyst

Choy Lye Chei – Japan Coordinator



  • Co-sponsorship
  • Co-funding the initial set up of ISAR

AstraZeneca: A global biopharmaceutical business delivering medicines to patients through innovative science and excellence in development and commercialisation.

The AstraZeneca Team

Marianna Alacqua – Head of Biologics, Global
Trung Tran – Director of Epidemiology
Ian Hirsch – Statistician
James Zangrilli – Global Medical Affairs

Observational and Pragmatic Research Institute (OPRI)

OPRI: Real world database research organization working to improve the understanding of risk-factors for poorly-controlled disease, the effectiveness of drugs, devices and patient management strategies in real life. OPRI ultimately aims to inform healthcare professionals on how to integrate and optimize these factors to drive better disease management.

Respiratory Effectiveness Group (REG)

  • Academic partner
  • Forum for discussion (REG Summit, Severe Asthma & Biomarkers Working Group)
  • Anonymized Data & Ethics Protocol Transparency (ADEPT) committee

REG: A not-for-profit investigator-led academic initiative comprising of over 420 respiratory/allergy experts globally collaborating on independent, academic real-life and comparative effectiveness research in respiratory medicine. 

The REG Team

Dermot Ryan – Director
Nicolas Roche – Executive Member
Michael Walker – Chief Operating Officer

Independent Governing Bodies

ISAR Steering Committee
  • Severe asthma renowned researchers from 21 countries and 4 AZ members
Respiratory Effectiveness Group (REG)
  • Academic partner
  • International severe asthma experts
ADEPT Committee
  • Research ethical oversight (operational for the past five years)
  • Senior researchers with clinical, epidemiological and/or database expertise
Operational Committee
  • Participating country representatives (country lead, data manager, etc.)