2021 Core Research Project (IGNITE) 2021 ISAR Global Research Project Effectiveness of biologics (by classes) in patients with different combination of T2 biomarkers (IGNITE) Objectives To describe the prevalence and overlap of elevated T2 biomarkers, related to specific T2 pathways (eosinophils (IL5), FeNO (IL13), IgE (IL4)), and the relationship between the T2 marker profile and the outcome of biological treatment. Project Lead Dr Celeste M. PorsbjergDr Trung N. Tran Ethics Registration ENCePP Approval:ADEPT Approval: