To describe the pattern of use and examine the impact on health outcomes of initiating biologic therapy in a real-world severe systemic corticosteroid-dependent asthma population.
To describe the demographic and clinical features of adult severe asthma population with high systemic corticosteroid (SCS) use (frequent rescue steroids or long-term oral corticosteroids), comparing between those who initiated a biologic therapy versus those who did not initiate biologics.
To assess the comparative effectiveness of initiating biologic therapy in adult severe asthma patients with high SCS use versus those that did not initiate biologics.