Biologics for severe asthma: time to switch it up?
Ever wondered about the pattern of use of biologics in real-life? Or whether the first biologic prescribed to a patient is the best one for that individual? This study explored these questions and more, using data from both ISAR and CHRONICLE and found, quite surprisingly, that even in a world with multiple biologic choices for severe asthma only about 11% of patients switched from one biologic to another and even a smaller proportion (10%) stopped. Interestingly if a change to biologic therapy was made, the pattern of switch vs ditch was country dependent. Some countries like the US, UK and Spain leaned towards stopping, while others like Kuwait, Bulgaria, Canada, Denmark, South Korea, Italy and Greece were more likely to switch. So, are we getting it right from the get-go, or are we under-switching?
Check out this figure to see the most common biologic switch patterns.
Ever wondered about the pattern of use of biologics in real-life? Or whether the first biologic prescribed to a patient is the best one for that individual? This study explored these questions and more, using data from both ISAR and CHRONICLE and found, quite surprisingly, that even in a world with multiple biologic choices for severe asthma only about 11% of patients switched from one biologic to another and even a smaller proportion (10%) stopped. Interestingly if a change to biologic therapy was made, the pattern of switch vs ditch was country dependent. Some countries like the US, UK and Spain leaned towards stopping, while others like Kuwait, Bulgaria, Canada, Denmark, South Korea, Italy and Greece were more likely to switch. So, are we getting it right from the get-go, or are we under-switching?
Check out this figure to see the most common biologic switch patterns.
Link to full article: https://lnkd.in/g2KRYG6E
Link to summary slide set: https://lnkd.in/g7ENk4sr
You can also see a summary of ISAR research: https://lnkd.in/g7ENk4sr
#severe asthma #ISAR #biologics #healthcare
Pattern of biologic switch (n=377)